It is essential to cast light on the construction risks in tunnel excavations through the fault-fracture zone (FFZ).This study adopts the material point method (MPM) to simulate the failure responses of a rock tunnel face during excavation through the FFZ.A numerical study was conducted to compare a physical model test and validate the feasibility
Self-expandable metal stent placement in a child for treatment of achalasia after failed Heller myotomy
Background and study aims Childhood achalasia treatment remains inconclusive.What is next after myotomy failure? Repeated pneumatic-dilation hindirochakkahaniya.com put patients at greater risk of perforation with possible symptom recurrence.We report on a 12-year-old patient with a 1-year history of achalasia whom underwent Heller myotomy with fun
(Arg)9-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling
Abstract Background Melanoma is a malignant tumor with high misdiagnosis rate and poor prognosis.The bio-targeted therapy is a prevailing method in the treatment of melanoma; however, bar drain board the accompanying drug resistance is inevitable.SH2 superbinder, a triple-mutant of the Src Homology 2 (SH2) domain, shows potent antitumor ability by
Interaction of BES1 and LBD37 transcription factors modulates brassinosteroid-regulated root forging response under low nitrogen in arabidopsis
Brassinosteriod (BR) plays important roles in regulation of plant growth, development and environmental underwater treasures sunken medallion responses.BR signaling regulates multiple biological processes through controlling the activity of BES1/BZR1 regulators.Apart from the roles in the promotion of plant growth, BR is also involved in regulation